SCHEMBL31336642

SCHEMBL31336642

[2H]C([2H])(N)[C@@H]1[C@H](C)OC(F)(F)CN1C(=O)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31336605 0.90 ALDH1A1 (0.32) USP2SMN1; SMN2
SCHEMBL31336719 0.87 NR1H2 (0.38) USP2SMN1; SMN2
SCHEMBL31336830 0.81
SCHEMBL31336643 0.78 KDM4E (0.34)
SCHEMBL31372444 0.75 NR1H2 (0.34) USP2SMN1; SMN2
SCHEMBL31336903 0.75 HCRTR1 (0.40)
SCHEMBL31336629 0.74 ALDH1A1 (0.35) SMN1; SMN2
SCHEMBL31336680 0.73 NR1H2 (0.34)
SCHEMBL31336954 0.70
SCHEMBL31336862 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688154-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - Portela & Ca., S.A. (PT) 2026-02-11 EP claimed
WO-2025023851-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - PORTELA & CA., S.A. (PT) 2025-01-30 WO claimed
EP-4688154-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - Portela & Ca., S.A. (PT) 2026-02-11 EP disclosed
WO-2025023851-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - PORTELA & CA., S.A. (PT) 2025-01-30 WO disclosed