SCHEMBL31337072

SCHEMBL31337072

COc1cccc2c(O)ccnc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.59
ADRA1D P25100 2/20 0.59
ADRA1A P35348 2/20 0.59
ADRA1B P35368 2/20 0.59
MEN1 O00255 3/20 0.48
HSP90AA1 P07900 3/20 0.48
KMT2A Q03164 3/20 0.48
NPC1 O15118 1/20 0.48
NSD2 O96028 1/20 0.48
CASP6 P55212 1/20 0.48
KDM4E B2RXH2 4/20 0.47
TP53 P04637 3/20 0.47
MAPT P10636 3/20 0.47
LMNA P02545 2/20 0.47
ALOX12 P18054 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2699726 1.00 HTR1A (0.59) HTR1AADRA1DADRA1AADRA1BMEN1
SCHEMBL9186410 0.86 KMT2A (0.55) HTR1AADRA1DADRA1AADRA1BMEN1
SCHEMBL3691358 0.83 HTR1A (0.45) HTR1AADRA1DADRA1AADRA1BMEN1
SCHEMBL3692922 0.81 KDM4E (0.45) HTR1AADRA1DADRA1AADRA1BMEN1
SCHEMBL13621091 0.80 SLC40A1 (0.42) HTR1AADRA1DADRA1AADRA1BMEN1
SCHEMBL1337689 0.80 HTR1A (0.61) HTR1AADRA1DADRA1AADRA1BNPC1
SCHEMBL16964453 0.79 HTR1A (0.60) HTR1AADRA1DADRA1AADRA1BNPC1
SCHEMBL7370612 0.79 HTR1A (0.59) HTR1AADRA1DADRA1AADRA1BHSP90AA1
SCHEMBL2178344 0.79 HTR1A (0.59) HTR1AADRA1DADRA1AADRA1BMEN1
SCHEMBL4014412 0.79 HTR1A (0.59) HTR1AADRA1DADRA1AADRA1BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113891879-B 3, 6-Disubstituted-2-pyridine aldoxime skeleton 国家科学研究中心 2025-03-04 CN disclosed