Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.41 |
| ▸ | PRKDC | P78527 | 4/20 | 0.41 |
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | HCK | P08631 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | MTOR | P42345 | 3/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23580425 | 1.00 | NOTUM (0.51) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL12647324 | 0.82 | NOTUM (0.51) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14167665 | 0.79 | PIK3CD (0.38) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL10260251 | 0.78 | PIK3CD (0.52) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL15147293 | 0.78 | NOTUM (0.49) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1923871 | 0.77 | NOTUM (0.48) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL12590760 | 0.77 | NOTUM (0.58) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL13019651 | 0.74 | YTHDC1 (0.46) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29255643 | 0.72 | NR3C1 (0.40) | NOTUMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL24121741 | 0.69 | XIAP (0.32) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |