Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118269 | 0.88 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DKMT2A | |
| SCHEMBL3128465 | 0.84 | PDE4A (0.44) | PDE4BPDE4APDE4CPDE4DGRIN1 | |
| SCHEMBL3129586 | 0.83 | PDE4A (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3132242 | 0.83 | FGFR1 (0.35) | PDE4BPDE4APDE4CPDE4DGRIN1 | |
| SCHEMBL3133720 | 0.82 | PDE4A (0.41) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3129299 | 0.82 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DGRIN1 | |
| SCHEMBL3203672 | 0.82 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DGRIN1 | |
| SCHEMBL3132289 | 0.81 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3199280 | 0.80 | PDE4B (0.36) | PDE4BPDE4APDE4CPDE4DKMT2A | |
| SCHEMBL3131213 | 0.79 | RXRA (0.50) | PDE4BPDE4APDE4CPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | claimed |
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |