Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995940 | 0.80 | LMNA (0.44) | MAPTL3MBTL1HPGDSMN1; SMN2TSHR | |
| SCHEMBL21590192 | 0.77 | LMNA (0.45) | L3MBTL1SMN1; SMN2TSHRCASP1CASP7 | |
| SCHEMBL31235679 | 0.74 | LMNA (0.56) | MAPTCYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8132928 | 0.74 | LMNA (0.56) | MAPTCYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21388018 | 0.74 | TSHR (0.41) | MAPTL3MBTL1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL29624394 | 0.74 | TSHR (0.41) | MAPTL3MBTL1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL15018736 | 0.72 | RAPGEF4 (0.38) | MAPTL3MBTL1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL28823865 | 0.72 | RAPGEF4 (0.38) | MAPTL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28092304 | 0.72 | TDP1 (0.38) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL2656784 | 0.71 | RAPGEF4 (0.37) | MAPTL3MBTL1SMN1; SMN2TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552171-A | Macrocyclic pyrazolopyrimidine compound and application thereof | 浙江养生堂天然药物研究所有限公司 | 2025-03-04 | — | — | CN | disclosed |