Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995940 | 0.77 | LMNA (0.44) | TDP1L3MBTL1SMN1; SMN2RAPGEF4TSHR | |
| SCHEMBL2656784 | 0.74 | RAPGEF4 (0.37) | L3MBTL1SMN1; SMN2RAPGEF4TSHRCASP1 | |
| SCHEMBL6938283 | 0.74 | KEAP1 (0.45) | SMN1; SMN2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL21388018 | 0.74 | TSHR (0.41) | L3MBTL1SMN1; SMN2RAPGEF4TSHRCASP1 | |
| SCHEMBL29624394 | 0.74 | TSHR (0.41) | L3MBTL1SMN1; SMN2RAPGEF4TSHRCASP1 | |
| Alcohol SCHEMBL7454876 | 0.73 | KMT2A (0.47) | L3MBTL1RAPGEF4HSD17B10ALDH1A1MAPT | |
| SCHEMBL28823865 | 0.72 | RAPGEF4 (0.38) | L3MBTL1SMN1; SMN2RAPGEF4TSHRCASP1 | |
| SCHEMBL15018736 | 0.72 | RAPGEF4 (0.38) | L3MBTL1SMN1; SMN2RAPGEF4TSHRCASP1 | |
| SCHEMBL31337347 | 0.72 | MAPT (0.41) | TDP1L3MBTL1SMN1; SMN2RAPGEF4TSHR | |
| SCHEMBL21590192 | 0.71 | LMNA (0.45) | TDP1L3MBTL1SMN1; SMN2RAPGEF4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509037-B | A kind of clopidogrel and the preparation method of intermediate thereof | 山东鲁药制药有限公司 | 2016-08-31 | — | — | CN | disclosed |