SCHEMBL3133843

SCHEMBL3133843

SC1NCN(c2ccccc2)N1c1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 4/20 0.42
▸ CYP2D6 P10635 2/20 0.42
▸ HTR6 P50406 2/20 0.42
▸ HTR7 P34969 2/20 0.42
▸ HTR3E A5X5Y0 1/20 0.42
▸ HTR3B O95264 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ HTR1A P08908 1/20 0.42
▸ NCF1 P14598 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ NFKB1 P19838 1/20 0.42
▸ HTR1D P28221 1/20 0.42
▸ HTR1B P28222 1/20 0.42
▸ HTR2A P28223 1/20 0.42
▸ MTOR P42345 1/20 0.42
▸ HTR3A P46098 1/20 0.42
▸ HTR5A P47898 1/20 0.42
▸ HTR3D Q70Z44 1/20 0.42
▸ HTR3C Q8WXA8 1/20 0.42
▸ SIGMAR1 Q99720 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3149834 0.80 SIGMAR1 (0.35) CYP2D6HTR3EHTR3BHTR3AHTR3D
SCHEMBL4296959 0.72 GAA (0.35) CYP1A2HTR1AHTR2ASIGMAR1ALDH1A1
SCHEMBL3150303 0.72 MEN1 (0.40) CYP2D6CYP1A2ALDH1A1HPGDMAPT
SCHEMBL3146473 0.69 BCHE (0.38) HTR3EHTR3BTSHRHTR1DHTR3A
SCHEMBL3146314 0.68 SIGMAR1 (0.34) HSD17B10HTR3EHTR3BTSHRNFKB1
SCHEMBL3133853 0.67 NPC1 (0.36) HSD17B10CYP2D6HTR6HTR7HTR3E
SCHEMBL3133847 0.64 HSD17B10 (0.36) HSD17B10CYP2D6HTR6HTR7HTR3E
SCHEMBL3146287 0.64 DRD4 (0.41) CYP2D6CYP1A2SIGMAR1ALDH1A1KMT2A
SCHEMBL9643856 0.63 HTR1A (0.74) HSD17B10CYP2D6HTR6HTR7HTR3E
Hydrochloric Acid SCHEMBL7203515 0.61 KDM4E (0.75) HSD17B10CYP2D6HTR6HTR7HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 — — EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 — — US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 — — US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
US-20090246699-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
EP-2090933-A1 Lithographic printing plate precursor and printing method FUJIFILM Corporation (JP) 2009-08-19 — — EP disclosed
US-20090197205-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 — — US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 — — US disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 — — EP disclosed
Send feedback