SCHEMBL3146314

SCHEMBL3146314

CN1C(S)NCN1c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 3/20 0.34
▸ HTR3E A5X5Y0 1/20 0.34
▸ HTR3B O95264 1/20 0.34
▸ ADRB1 P08588 1/20 0.34
▸ HTR3A P46098 1/20 0.34
▸ HTR3D Q70Z44 1/20 0.34
▸ HTR3C Q8WXA8 1/20 0.34
▸ DRD2 P14416 1/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ TSHR P16473 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ G6PD P11413 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ CHRNA7 P36544 3/20 0.32
▸ MAPK1 P28482 2/20 0.32
▸ CHRNB2 P17787 2/20 0.32
▸ CHRNA3 P32297 2/20 0.32
▸ CHRNA4 P43681 2/20 0.32
▸ CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3149834 0.79 SIGMAR1 (0.35) SIGMAR1HTR3EHTR3BADRB1HTR3A
SCHEMBL3144726 0.76 DRD2 (0.37) SIGMAR1DRD2SMN1; SMN2NPC1RAB9A
SCHEMBL3141469 0.75 MAPK1 (0.36) ADRB1KMT2ATSHRMAPK1POLB
SCHEMBL8744604 0.74 SIGMAR1 (0.34) SIGMAR1HTR3EHTR3BADRB1HTR3A
SCHEMBL3840283 0.74 HTR1A (0.44) SIGMAR1DRD2
SCHEMBL3145238 0.73 ALDH1A1 (0.41) TSHRL3MBTL1MAPK1CYP3A4SMN1; SMN2
SCHEMBL3146287 0.73 DRD4 (0.41) SIGMAR1DRD2KMT2AGAACYP3A4
SCHEMBL3150303 0.71 MEN1 (0.40) KMT2AGAAL3MBTL1MAPK1CYP3A4
SCHEMBL4296959 0.71 GAA (0.35) SIGMAR1DRD2KMT2AGAAALOX5
SCHEMBL3146473 0.68 BCHE (0.38) SIGMAR1HTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 — — EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 — — US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 — — US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
US-20090246699-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
EP-2090933-A1 Lithographic printing plate precursor and printing method FUJIFILM Corporation (JP) 2009-08-19 — — EP disclosed
US-20090197205-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 — — US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 — — US disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 — — EP disclosed
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