Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31338812 | 0.82 | FNTA (0.54) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL30708759 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL26931196 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL27156313 | 0.78 | NOD2 (0.44) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL31338810 | 0.78 | FNTA (0.56) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL27211468 | 0.76 | ALDH1A1 (0.47) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL31338818 | 0.76 | FNTA (0.42) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL1523174 | 0.75 | ALDH1A1 (0.67) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL24748610 | 0.75 | ALDH1A1 (0.46) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL31338813 | 0.75 | KMT2A (0.40) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12194029-B1 | Ethyl-1-(substitutedbenzoyl)-5-methylpyrrolo[1,2-a]quinoline-3-carboxylates as anticancer agents | King Faisal University (SA) | 2025-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12194029-B1 | Ethyl-1-(substitutedbenzoyl)-5-methylpyrrolo[1,2-a]quinoline-3-carboxylates as anticancer agents | TOP2A, TOP1, TP53 | ALDH1A1 309/4885GAA 842/4885SMN1; SMN2 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.