Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 5/20 | 0.41 |
| ▸ | FNTB | P49356 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24748610 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAASMN1; SMN2HPGDGLA | |
| SCHEMBL31338823 | 0.76 | ALDH1A1 (0.45) | ALDH1A1GAASMN1; SMN2KDM4EHPGD | |
| SCHEMBL27211444 | 0.76 | ALDH1A1 (0.51) | ALDH1A1GAASMN1; SMN2KDM4EHPGD | |
| SCHEMBL27211499 | 0.76 | FNTA (0.52) | ALDH1A1GAASMN1; SMN2KDM4EHPGD | |
| SCHEMBL27211517 | 0.76 | FNTA (0.52) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL26931196 | 0.75 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2KDM4EHPGD | |
| SCHEMBL30708759 | 0.75 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2KDM4EHPGD | |
| SCHEMBL27211503 | 0.75 | BCHE (0.52) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL1523174 | 0.75 | ALDH1A1 (0.67) | ALDH1A1GAASMN1; SMN2HPGDGLA | |
| SCHEMBL27156313 | 0.73 | NOD2 (0.44) | ALDH1A1GAASMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976066-B1 | Substituted 7-amino-3-(substituted benzoyl)indolizine-1-carboxylates as anti-tubercular agents | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11976066-B1 | Substituted 7-amino-3-(substituted benzoyl)indolizine-1-carboxylates as anti-tubercular agents | BET1, INMT, IDO1 | ALDH1A1 612/4885GAA 1199/4885SMN1; SMN2 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.