Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25274630 | 1.00 | GPR119 (0.56) | GPR119HPGDSHSD11B1PRMT5WDR77 | |
| SCHEMBL30417389 | 0.94 | GPR119 (0.60) | GPR119HPGDSHSD11B1LMNAMAPT | |
| SCHEMBL14497248 | 0.94 | GPR119 (0.60) | GPR119HPGDSHSD11B1LMNAMAPT | |
| SCHEMBL4705282 | 0.90 | GPR119 (0.52) | GPR119HPGDSHSD11B1ALDH1A1CHRNA7 | |
| SCHEMBL30098458 | 0.89 | GPR119 (0.55) | GPR119HSD11B1ALDH1A1MAPTCYP11B2 | |
| SCHEMBL20757936 | 0.89 | GPR119 (0.55) | GPR119HSD11B1ALDH1A1MAPTCYP11B2 | |
| SCHEMBL3154994 | 0.86 | GPR119 (0.65) | GPR119HSD11B1MAPTKDM4E | |
| SCHEMBL25343613 | 0.85 | PDE4B (0.52) | GPR119HPGDSHSD11B1PRMT5ALDH1A1 | |
| SCHEMBL26667052 | 0.85 | PDE4B (0.52) | GPR119HPGDSHSD11B1PRMT5ALDH1A1 | |
| SCHEMBL6359096 | 0.85 | ALDH1A1 (0.56) | GPR119HPGDSPRMT5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |