Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697513 | 0.93 | TP53 (0.59) | ALDH1A1LMNAHPGDHPGDSUSP30 | |
| SCHEMBL23951735 | 0.93 | TP53 (0.59) | ALDH1A1LMNAHPGDHPGDSUSP30 | |
| SCHEMBL1751432 | 0.93 | TP53 (0.59) | ALDH1A1LMNAHPGDHPGDSUSP30 | |
| SCHEMBL22944633 | 0.92 | USP30 (0.59) | ALDH1A1LMNAHPGDHIF1AHPGDS | |
| SCHEMBL24350753 | 0.90 | GPR119 (0.55) | ALDH1A1LMNAHPGDHIF1AHPGDS | |
| SCHEMBL22944331 | 0.90 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDHIF1AHPGDS | |
| SCHEMBL22945386 | 0.89 | USP30 (0.64) | HPGDSUSP30PDE4BPRMT5ACKR3 | |
| SCHEMBL1935816 | 0.88 | HSD11B1 (0.61) | ALDH1A1LMNAHPGDHIF1AHPGDS | |
| SCHEMBL20748135 | 0.88 | PDE4B (0.53) | ALDH1A1LMNAHPGDHIF1AHPGDS | |
| SCHEMBL28301552 | 0.88 | PDE4B (0.53) | ALDH1A1LMNAHPGDHIF1AHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236423-B | Piperidinyl-3- (aryloxy) propanamides and propionic acid esters | 武田药品工业株式会社 | 2024-02-06 | — | — | CN | disclosed |
| EP-4138824-A1 | LOX ENZYME INHIBITING METHODS AND COMPOSITIONS | Anovia Biosciences, Inc. (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |
| CN-112236423-A | Piperidinyl-3- (aryloxy) propanamides and propionates | 武田药品工业株式会社 | 2021-01-15 | — | — | CN | disclosed |
| US-20170226105-A1 | TIED-BACK BENZAMIDE DERIVATIVES AS POTENT ROCK INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-08-10 | — | — | US | disclosed |
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226105-A1 | TIED-BACK BENZAMIDE DERIVATIVES AS POTENT ROCK INHIBITORS | MYLK, ROCK1, MYLK2 | ALDH1A1 2362/4885LMNA 676/4885HPGD 2893/4885 |
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | ALDH1A1 199/4885LMNA 4720/4885HPGD 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.