Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609125 | 1.00 | MTOR (0.48) | MTORPIK3CAPIK3CDSMN1; SMN2CHEK1 | |
| SCHEMBL1608915 | 0.95 | MTOR (0.52) | MTORPIK3CAPIK3CDSMN1; SMN2CHEK1 | |
| SCHEMBL25534545 | 0.87 | ALDH1A1 (0.44) | MTORPIK3CAPIK3CDSMN1; SMN2MAPK1 | |
| SCHEMBL17589999 | 0.83 | SMN1; SMN2 (0.42) | MTORPIK3CAPIK3CDSMN1; SMN2MAPK1 | |
| SCHEMBL23287625 | 0.80 | SMN1; SMN2 (0.39) | MTORSMN1; SMN2CHEK1PDPK1MAPK1 | |
| SCHEMBL1609664 | 0.79 | MTOR (0.53) | MTORPIK3CAPIK3CDCHEK1 | |
| SCHEMBL1608742 | 0.79 | MTOR (0.53) | MTORPIK3CAPIK3CDCHEK1 | |
| SCHEMBL1608745 | 0.79 | MTOR (0.53) | MTORPIK3CAPIK3CDCHEK1 | |
| SCHEMBL30366120 | 0.77 | PIK3CA (0.60) | MTORPIK3CASMN1; SMN2POLBTSHR | |
| SCHEMBL358366 | 0.77 | PIK3CA (0.60) | MTORPIK3CASMN1; SMN2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |