Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10249024 | 0.83 | SMN1; SMN2 (0.47) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL3714642 | 0.83 | PDE10A (0.56) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL429041 | 0.82 | MEN1 (0.51) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL13515552 | 0.82 | ATM (0.49) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL17896693 | 0.81 | PDE10A (0.50) | MEN1KMT2ARAB9AMAPTKDM4E | |
| SCHEMBL10176223 | 0.81 | SMN1; SMN2 (0.50) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL17896660 | 0.79 | CYP11B2 (0.43) | ATMNPC1RAB9ATP53MAPT | |
| SCHEMBL167106 | 0.79 | PDE10A (0.46) | ATMSMN1; SMN2CYP11B2POLBCYP11B1 | |
| SCHEMBL17896744 | 0.78 | CYP11B2 (0.47) | ATMNPC1RAB9ATP53MAPT | |
| SCHEMBL10175104 | 0.78 | CYP11B2 (0.45) | SMN1; SMN2CYP11B2POLBCYP11B1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119365192-A | Heteroaryl compounds as HPK1 inhibitors and methods of use thereof | 深圳市原力深湾创新药有限公司 | 2025-01-24 | — | — | CN | disclosed |