SCHEMBL31339930

SCHEMBL31339930

Cc1cc(Cl)ncc1-n1c(=O)c(C(=O)O)cc2ccc(C(F)(F)F)nc21

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 7/20 0.37
RXRA P19793 1/20 0.36
SYK P43405 3/20 0.36
KDM4E B2RXH2 1/20 0.33
TAS2R14 Q9NYV8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30489830 0.79 MAT2A (0.56) MAT2ASYKTAS2R14
SCHEMBL31339936 0.77 MAT2A (0.43) MAT2ASYKTAS2R14
SCHEMBL31042304 0.75 MAT2A (0.41) MAT2A
SCHEMBL31339894 0.75 SYK (0.39) MAT2ASYKTAS2R14
SCHEMBL31339862 0.75 SYK (0.38) MAT2ASYK
SCHEMBL1372402 0.75 TAS2R14 (0.39) MAT2ARXRAKDM4ETAS2R14
SCHEMBL31339858 0.74 THRB (0.41) MAT2ASYKKDM4ETAS2R14
Hydrochloric Acid SCHEMBL1372411 0.74 TAS2R14 (0.39) MAT2ARXRAKDM4ETAS2R14
SCHEMBL31339926 0.73 MAT2A (0.41) MAT2ASYKTAS2R14
SCHEMBL31554412 0.72 NOTUM (0.40) RXRAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4501912-A1 NOVEL HETEROCYCLIC COMPOUND Shouyao Holdings (Beijing) Co., Ltd. (CN) 2025-02-05 EP disclosed