Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | S100A9 | P06702 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27196885 | 0.83 | KMT2A (0.65) | KMT2AAXLS100A9ADORA3ADORA1 | |
| SCHEMBL30498458 | 0.83 | KMT2A (0.65) | KMT2AAXLS100A9ADORA3ADORA1 | |
| SCHEMBL31340941 | 0.81 | KMT2A (0.43) | KMT2AAXL | |
| SCHEMBL31340871 | 0.76 | NR2F2 (0.51) | KMT2AJAK3 | |
| SCHEMBL31340957 | 0.71 | KMT2A (0.36) | KMT2AJAK2JAK3 | |
| SCHEMBL2516929 | 0.70 | KMT2A (0.55) | KMT2AAXLADORA3ADORA1ADORA2A | |
| SCHEMBL844926 | 0.70 | KMT2A (0.58) | KMT2AAXLJAK2JAK3ADORA3 | |
| SCHEMBL16914307 | 0.69 | S100A9 (0.45) | KMT2AS100A9JAK2 | |
| SCHEMBL29608859 | 0.68 | KMT2A (0.60) | KMT2AAXLADORA3ADORA1ADORA2A | |
| SCHEMBL13812813 | 0.68 | KMT2A (0.65) | KMT2AAXLADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049247-A1 | 5,6-CORE SILACYCLE BASED INHIBITORS OF DNA-DEPENDENT PROTEIN KINASE AND COMPOSITIONS AND APPLICATION IN GENE EDITING | JUNO THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |