Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12761617 | 0.89 | CA2 (0.34) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL19352538 | 0.83 | EPHX1 (0.39) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL2975382 | 0.83 | HDAC4 (0.41) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL5479772 | 0.83 | HDAC4 (0.41) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL20830172 | 0.83 | EPHX1 (0.39) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL2975383 | 0.83 | HDAC4 (0.41) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL16393079 | 0.82 | ALDH1A1 (0.36) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL21418776 | 0.82 | ESR1 (0.33) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL18342243 | 0.82 | CYP2D6 (0.38) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL24371436 | 0.80 | EPHX1 (0.44) | CA2ALDH1A1MEN1KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072637-A1 | OXYGENATED HETEROCYCLIC LSD-1 INHIBITORS AND RELATED METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-04-03 | — | — | WO | disclosed |
| US-12006307-B2 | Pharmaceutical compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| US-20230071620-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-03-09 | — | — | US | disclosed |
| US-20230071620-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-03-09 | — | — | US | disclosed |
| US-11447465-B2 | Pharmaceutical compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| WO-2018160891-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICAL, INC. (US) | 2018-09-07 | — | — | WO | disclosed |
| US-9435796-B2 | Cyanine dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9435796-B2 | Cyanine dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-20140273010-A1 | ACID-CLEAVABLE AND CLICKABLE AFFINITY CAPTURE PROBE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140273010-A1 | ACID-CLEAVABLE AND CLICKABLE AFFINITY CAPTURE PROBE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-09-18 | — | — | US | disclosed |
| US-7705150-B2 | Cyanine dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-7641914-B2 | for forming conjugates (liposomes, complexes, nanoparticles) with biologically active substances and releasing them into cellular tissues or acidic compartments, or for use as nonionic surfactant for stabilizing particles encapsulating biodrugs | GENCELL, S.A. (FR) | 2010-01-05 | — | — | US | disclosed |
| EP-1317439-B1 | ACID-SENSITIVE COMPOUNDS, PREPARATION AND USES THEREOF | CENTELION (FR) | 2005-12-07 | — | — | EP | disclosed |
| US-20050222434-A1 | Acid-sensitive compounds, their preparation and uses | GENCELL S.A. | 2005-10-06 | — | — | US | disclosed |
| US-20050085426-A1 | Acid-sensitive compounds, preparation and use thereof | GENCELL S.A.S. (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1317439-A1 | ACID-SENSITIVE COMPOUNDS, PREPARATION AND USES THEREOF | GENCELL S.A. (FR) | 2003-06-11 | — | — | EP | disclosed |
| US-20020091242-A1 | Acid-sensitive compounds, their preparation and uses | GENCELL S.A. (FR) | 2002-07-11 | — | — | US | disclosed |
| WO-2002020510-A1 | ACID-SENSITIVE COMPOUNDS, PREPARATION AND USES THEREOF | GENCELL S.A. (FR) | 2002-03-14 | — | — | WO | disclosed |
| EP-0819134-B1 | COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES, METHOD FOR PREPARING SAME, AND SYNTHON USED THEREIN | GENSET SA (FR) | 2001-07-18 | — | — | EP | disclosed |
| US-6187913-B1 | Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method | GENSET (FR) | 2001-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222434-A1 | Acid-sensitive compounds, their preparation and uses | LIPA, PHOSPHO1, ACP1 | CA2 357/4885ALDH1A1 1301/4885POLB 4001/4885 |
| US-20050085426-A1 | Acid-sensitive compounds, preparation and use thereof | LIPA, PHOSPHO1, ABHD16A | CA2 518/4885ALDH1A1 1138/4885POLB 3735/4885 |
| US-20020091242-A1 | Acid-sensitive compounds, their preparation and uses | LIPA, PHOSPHO1, ACP1 | CA2 357/4885ALDH1A1 1301/4885POLB 4001/4885 |
| US-12006307-B2 | Pharmaceutical compounds for treatment of medical disorders | CFD, TFPI, CFH | CA2 2355/4885ALDH1A1 3105/4885POLB 2864/4885 |
| US-20230071620-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | CFD, TFPI, CFH | CA2 2355/4885ALDH1A1 3105/4885POLB 2864/4885 |
| US-11447465-B2 | Pharmaceutical compounds for treatment of medical disorders | CFD, TFPI, CFH | CA2 2355/4885ALDH1A1 3105/4885POLB 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.