Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342834 | 0.86 | CYP3A4 (0.40) | NR1H2NR1H3GPR119CYP3A4KIT | |
| SCHEMBL31343028 | 0.82 | CYP3A4 (0.38) | NR1H2NR1H3GPR119CYP3A4SLC6A9 | |
| Hydrochloric Acid SCHEMBL31342952 | 0.77 | ACVR1B (0.32) | KCNH2 | |
| SCHEMBL31342982 | 0.77 | GPR119 (0.42) | GPR119 | |
| SCHEMBL31342951 | 0.76 | CYP3A4 (0.41) | GPR119CYP3A4KCNH2SLC6A9 | |
| SCHEMBL31342893 | 0.76 | CYP3A4 (0.39) | NR1H2NR1H3GPR119CYP3A4KCNH2 | |
| SCHEMBL31342923 | 0.75 | CYP3A4 (0.52) | GPR119CYP3A4 | |
| SCHEMBL31342949 | 0.74 | CYP3A4 (0.51) | GPR119CYP3A4 | |
| SCHEMBL31342995 | 0.72 | CYP3A4 (0.39) | GPR119CYP3A4KIT | |
| SCHEMBL31342999 | 0.70 | CYP3A4 (0.53) | GPR119CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |