SCHEMBL3134368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3130660	0.99	HSD11B1 (0.47)	HSD11B1ALDH1A1MEN1KMT2APOLB
	SCHEMBL15946026	0.89	HSD11B1 (0.44)	HSD11B1ALDH1A1MEN1KMT2APOLB
	SCHEMBL15945998	0.88	HTR2B (0.45)	HSD11B1ALDH1A1MEN1KMT2APOLB
	SCHEMBL13355610	0.86	ALDH1A1 (0.43)	HSD11B1ALDH1A1MEN1KMT2APOLB
	SCHEMBL2150924	0.85	ALDH1A1 (0.42)	HSD11B1ALDH1A1MEN1KMT2APOLB
	SCHEMBL3133186	0.80	ALDH1A1 (0.47)	ALDH1A1MEN1KMT2APOLBCA1
	SCHEMBL3136938	0.79	CA1 (0.43)	HSD11B1ALDH1A1MEN1KMT2APOLB
	SCHEMBL3088255	0.79	HSD11B1 (0.57)	HSD11B1ALDH1A1MEN1KMT2APOLB
	SCHEMBL13323820	0.79	CA1 (0.43)	HSD11B1ALDH1A1MEN1KMT2APOLB
	SCHEMBL27972215	0.78	KCNK3 (0.52)	HSD11B1ALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.