Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 1.00 |
| ▸ | GAA | P10253 | 17/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 7/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077294 | 1.00 | MAPT (1.00) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL31344185 | 0.88 | MAPT (0.79) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL10077268 | 0.88 | MAPT (1.00) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL19569163 | 0.86 | MAPT (0.83) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL10077266 | 0.86 | MAPT (1.00) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL14016030 | 0.85 | MAPT (0.75) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL19568911 | 0.82 | MAPT (1.00) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL2252757 | 0.82 | MAPT (0.69) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL10077270 | 0.82 | GAA (1.00) | MAPTGAAKDM4EMAPK1TP53 | |
| SCHEMBL10077293 | 0.81 | MAPT (1.00) | MAPTGAAKDM4EMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240408072-A1 | COMPOSITION FOR PREVENTING OR TREATING GRAVES' DISEASE COMPRISING COMPOUND CONTAINING AN IMIDAZOPYRIDINE STRUCTURE AS ACTIVE INGREDIENT | ESGELBIO INC. (KR) | 2024-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240408072-A1 | COMPOSITION FOR PREVENTING OR TREATING GRAVES' DISEASE COMPRISING COMPOUND CONTAINING AN IMIDAZOPYRIDINE STRUCTURE AS ACTIVE INGREDIENT | TPO, GIPR, TRHDE | MAPT 4662/4885GAA 467/4885KDM4E 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.