SCHEMBL31344362

SCHEMBL31344362

Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(=O)c3cc(Cl)ccc32)c(C)c1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AVPR2 P30518 13/20 0.70
AVPR1A P37288 3/20 0.70
ABCB11 O95342 1/20 0.70
ADRB2 P07550 1/20 0.70
HTR1A P08908 1/20 0.70
ADORA3 P0DMS8 1/20 0.70
CHRM1 P11229 1/20 0.70
TBXA2R P21731 1/20 0.70
HTR2C P28335 1/20 0.70
HRH1 P35367 1/20 0.70
OPRM1 P35372 1/20 0.70
GLP1R P43220 1/20 0.70
TMEM97 Q5BJF2 1/20 0.70
FFAR4 Q5NUL3 1/20 0.70
GPR119 Q8TDV5 1/20 0.70
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
OXTR P30559 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL533754 1.00 AVPR2 (0.70) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL30354671 1.00 AVPR2 (0.70) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL14962830 0.92 AVPR2 (0.67) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL12076284 0.91 AVPR2 (0.61) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL26405946 0.91 AVPR2 (0.68) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL20407284 0.87 AVPR2 (0.71) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL12076275 0.86 AVPR2 (0.60) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL7351642 0.86 AVPR2 (0.57) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL28625477 0.85 AVPR2 (0.51) AVPR2AVPR1AABCB11ADRB2HTR1A
SCHEMBL26405907 0.84 AVPR2 (0.60) AVPR2AVPR1AABCB11ADRB2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119310215-B Method for detecting impurity content in tolvaptan sodium phosphate freeze-dried powder injection 珠海前列药业有限公司 2025-03-14 CN claimed
CN-119310215-A Method for detecting impurity content in tolvaptan sodium phosphate freeze-dried powder injection 珠海前列药业有限公司 2025-01-14 CN claimed
CN-119310215-B Method for detecting impurity content in tolvaptan sodium phosphate freeze-dried powder injection 珠海前列药业有限公司 2025-03-14 CN disclosed
CN-119310215-A Method for detecting impurity content in tolvaptan sodium phosphate freeze-dried powder injection 珠海前列药业有限公司 2025-01-14 CN disclosed