Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 7/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRF1 | P14222 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134581 | 1.00 | TDP1 (0.55) | TDP1PTPN1PTPN22TNFRSF1AHPGD | |
| SCHEMBL3134593 | 1.00 | TDP1 (0.55) | TDP1PTPN1PTPN22TNFRSF1AHPGD | |
| SCHEMBL3135714 | 0.82 | TNFRSF1A (0.57) | TDP1PTPN1PTPN22TNFRSF1AMEN1 | |
| SCHEMBL3135718 | 0.82 | TNFRSF1A (0.57) | TDP1PTPN1PTPN22TNFRSF1AMEN1 | |
| SCHEMBL3135706 | 0.82 | TNFRSF1A (0.57) | TDP1PTPN1PTPN22TNFRSF1AMEN1 | |
| SCHEMBL12177152 | 0.76 | PPARG (0.60) | TDP1PTPN1PTPN22ALDH1A1PPARG | |
| SCHEMBL3133011 | 0.76 | ITGB2 (0.60) | TNFRSF1AMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL3133014 | 0.76 | ITGB2 (0.60) | TNFRSF1AMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL3133007 | 0.76 | ITGB2 (0.60) | TNFRSF1AMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL12177157 | 0.75 | ALDH1A1 (0.52) | TDP1PTPN22HPGDMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | claimed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | claimed |
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | MAVS, LAMP1, HAVCR2 | TDP1 1886/4885PTPN1 1273/4885PTPN22 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.