Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135714 | 1.00 | TNFRSF1A (0.57) | TNFRSF1ATDP1PTPN22PTPN1MAPK1 | |
| SCHEMBL3135718 | 1.00 | TNFRSF1A (0.57) | TNFRSF1ATDP1PTPN22PTPN1MAPK1 | |
| SCHEMBL25165760 | 0.88 | TNFRSF1A (0.62) | TNFRSF1APTPN22MAPK1ALDH1A1POLB | |
| SCHEMBL13056341 | 0.85 | PTPN22 (0.70) | PTPN22PTPN1POLBMEN1KMT2A | |
| SCHEMBL7860609 | 0.83 | TNFRSF1A (0.55) | TNFRSF1AMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3134588 | 0.82 | TDP1 (0.55) | TNFRSF1ATDP1PTPN22PTPN1MAPK1 | |
| SCHEMBL3134593 | 0.82 | TDP1 (0.55) | TNFRSF1ATDP1PTPN22PTPN1MAPK1 | |
| SCHEMBL3134581 | 0.82 | TDP1 (0.55) | TNFRSF1ATDP1PTPN22PTPN1MAPK1 | |
| SCHEMBL7862697 | 0.81 | NLRP3 (0.64) | PTPN1MAPK1ALDH1A1POLBMEN1 | |
| SCHEMBL3135408 | 0.80 | KMT2A (0.58) | PTPN1POLBMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | claimed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | claimed |
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | MAVS, LAMP1, HAVCR2 | TNFRSF1A 2355/4885TDP1 1886/4885PTPN22 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.