SCHEMBL31346004

SCHEMBL31346004

N/C(=N\O)c1cccc(C2Cc3cc(Cl)c(F)cc3O2)n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.31
TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346049 0.79 CYP11B1 (0.36)
SCHEMBL31346074 0.78 DPP4 (0.30) DPP4TTR
SCHEMBL31346069 0.78 KDM1A (0.36) TTR
SCHEMBL31346081 0.78 EZH2 (0.33)
SCHEMBL31346115 0.76 CTSS (0.36)
SCHEMBL31346064 0.73 TTR (0.31) TTR
SCHEMBL31346027 0.72
SCHEMBL31346035 0.70 SLC6A2 (0.36)
SCHEMBL31345970 0.68 TTR (0.32) TTR
SCHEMBL31346103 0.66 FFAR1 (0.35) TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed