SCHEMBL31346115

SCHEMBL31346115

N#Cc1cccc(C2Cc3cc(Cl)c(F)cc3O2)n1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSS P25774 3/20 0.36
CTSK P43235 1/20 0.32
USP30 Q70CQ3 3/20 0.31
DRD4 P21917 2/20 0.31
HTR1A P08908 1/20 0.31
DRD2 P14416 1/20 0.31
LDHA P00338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346124 0.90 CTSK (0.35) CTSSCTSKUSP30DRD4HTR1A
SCHEMBL31346074 0.82 DPP4 (0.30)
SCHEMBL31346014 0.77 CTSS (0.47) CTSSCTSK
SCHEMBL31346087 0.76 EZH2 (0.36) CTSSCTSKUSP30DRD4LDHA
SCHEMBL31346143 0.76 LDHA (0.46) DRD2LDHA
SCHEMBL31346004 0.76 DPP4 (0.31)
SCHEMBL31346104 0.75 DRD2 (0.34) USP30DRD4DRD2
SCHEMBL31346027 0.75
SCHEMBL31346003 0.74 CTSS (0.42) CTSSCTSK
SCHEMBL31346116 0.73 LDHA (0.33) LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed