SCHEMBL31346141

SCHEMBL31346141

Clc1cc(Cl)c2c(c1)CC(c1cccc(Br)n1)O2

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EZH2 Q15910 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346083 0.84 TEAD1 (0.33)
SCHEMBL31346145 0.84 TEAD1 (0.33)
SCHEMBL31346087 0.81 EZH2 (0.36) EZH2
SCHEMBL31345970 0.78 TTR (0.32)
SCHEMBL31346081 0.77 EZH2 (0.33) EZH2
SCHEMBL31346055 0.76 EZH2 (0.39) EZH2
SCHEMBL31346016 0.75 KMO (0.37) EZH2
SCHEMBL31346074 0.74 DPP4 (0.30)
SCHEMBL31346169 0.68 CYP19A1 (0.49) EZH2
SCHEMBL31346047 0.67 TEAD1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed