Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346262 | 0.85 | KDM4E (0.45) | ADORA2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2820462 | 0.76 | ADORA2A (0.67) | ADORA2ASYKALDH1A1KDM4EMAPT | |
| SCHEMBL29892468 | 0.74 | ALDH1A1 (0.55) | ADORA2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2162709 | 0.73 | ADORA2A (0.56) | ADORA2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31346225 | 0.68 | FLT3 (0.61) | ADORA2ASYKALDH1A1KDM4EMAPT | |
| SCHEMBL11734135 | 0.68 | KDM4E (0.50) | ADORA2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL22651970 | 0.68 | RAB9A (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL2817059 | 0.68 | MAPT (0.47) | ADORA2ASYKALDH1A1KDM4EMAPT | |
| SCHEMBL31612370 | 0.67 | RAD51 (0.68) | ADORA2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL2818200 | 0.67 | ADORA2A (0.52) | ADORA2AALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423763-B | Regioselective synthesis of imidazo [1,2-a ] pyrimidines | 豪夫迈·罗氏有限公司 | 2025-01-21 | — | — | CN | disclosed |