Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557192 | 0.85 | CTSS (0.56) | KMT2AMEN1CTSSCTSKCA2 | |
| SCHEMBL31075491 | 0.85 | CTSS (0.56) | KMT2AMEN1CTSSCTSKCA2 | |
| SCHEMBL11036298 | 0.81 | HDAC4 (0.53) | KMT2AMEN1CTSSCTSKCA2 | |
| SCHEMBL6555098 | 0.81 | CTSS (0.56) | KMT2AMEN1CTSSCTSKCA2 | |
| SCHEMBL23975809 | 0.80 | CTSS (0.61) | CTSSCTSKCA2HDAC4HDAC1 | |
| SCHEMBL7414154 | 0.80 | CTSS (0.61) | CTSSCTSKCA2HDAC4HDAC1 | |
| SCHEMBL7414151 | 0.80 | CTSS (0.61) | CTSSCTSKCA2HDAC4HDAC1 | |
| SCHEMBL21585117 | 0.80 | CA2 (0.56) | KMT2AMEN1CTSSCTSKCA2 | |
| SCHEMBL6555039 | 0.79 | HDAC4 (0.55) | KMT2AMEN1CTSSCTSKCA2 | |
| SCHEMBL21585118 | 0.79 | CA2 (0.55) | KMT2AMEN1CTSSCTSKCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021189-A1 | OXYGEN-CONTAINING FUSED TRICYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海拓界生物医药科技有限公司 | 2025-01-30 | — | — | WO | disclosed |