SCHEMBL31347321

SCHEMBL31347321

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccc(OC(C)(C)C)cc1)C(=O)N[C@@H](CC(=O)OC(C)(C)C)C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 6/20 0.41
▸ OPRM1 P35372 5/20 0.41
▸ OPRD1 P41143 5/20 0.41
▸ REN P00797 3/20 0.41
▸ CPB1 P15086 1/20 0.40
▸ CPB2 Q96IY4 1/20 0.40
▸ NPY4R P50391 5/20 0.40
▸ NPY1R P25929 4/20 0.40
▸ NPY2R P49146 3/20 0.39
▸ NPY5R Q15761 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29665650 0.88 NPY4R (0.42) OPRK1OPRM1OPRD1NPY4RNPY1R
SCHEMBL30082288 0.85 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29468869 0.84 VIPR2 (0.42) OPRK1OPRM1OPRD1
SCHEMBL31510099 0.84 CTSL (0.47) OPRK1RENNPY4RNPY1RNPY2R
SCHEMBL30541993 0.83 OPRM1 (0.46) OPRK1OPRM1OPRD1
SCHEMBL30202260 0.81 NPY4R (0.46) OPRK1RENNPY4RNPY1RNPY2R
SCHEMBL21981319 0.80 REN (0.53) OPRK1RENCPB1CPB2NPY4R
SCHEMBL21981320 0.80 REN (0.53) OPRK1RENCPB1CPB2NPY4R
SCHEMBL30202298 0.80 NPY4R (0.51) RENNPY4RNPY1RNPY2RNPY5R
SCHEMBL31094178 0.80 CTSL (0.46) OPRM1OPRD1RENNPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724472-A2 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS Sun Pharmaceutical Industries Limited (IN) 2026-04-15 — — EP disclosed
WO-2024252367-A2 NOVEL GLP-1/GIP DUAL AND GLP-1/GCG DUAL RECEPTOR AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-12-12 — — WO disclosed
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