Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3737689 | 0.92 | SGMS2 (0.34) | SGMS2HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL1697182 | 0.84 | ADRA2A (0.33) | ADRA2AADRA2BADRA2C | |
| SCHEMBL28360867 | 0.83 | CYP2D6 (0.40) | HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL28157161 | 0.82 | TLR8 (0.35) | — | |
| SCHEMBL16241390 | 0.81 | SGMS2 (0.32) | SGMS2 | |
| SCHEMBL404719 | 0.77 | PPARG (0.31) | — | |
| SCHEMBL2018228 | 0.77 | MEN1 (0.32) | ADRA2AADRA2BADRA2C | |
| SCHEMBL5713157 | 0.76 | PDE5A (0.40) | SGMS2HTR1AADRA2A | |
| SCHEMBL118831 | 0.76 | TLR8 (0.36) | HTR1A | |
| SCHEMBL25315303 | 0.76 | PPARG (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2015727-B1 | WATER RESISTANT SUNSCREEN FORMULATIONS WITH SULFOPOLYESTERS AND PHOSPHATE ESTER SURFACTANTS | EASTMAN CHEM CO (US) | 2010-01-06 | — | — | EP | disclosed |
| US-20070264216-A1 | Water resistant sunscreen formulas with sulfopolyesters and phosphate ester surfactants | EASTMAN CHEMICAL COMPANY | 2007-11-15 | — | — | US | disclosed |