SCHEMBL404719

SCHEMBL404719

CCCCCC(CC)Oc1ccccc1C(Oc1ccccc1-c1ccnnn1)c1ccccc1OC(CC)CCCCC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697182 0.92 ADRA2A (0.33) PPARG
SCHEMBL25315303 0.91 PPARG (0.31) PPARG
SCHEMBL21525742 0.86 PPARG (0.31) PPARG
SCHEMBL20607656 0.85 MCHR1 (0.32) PPARG
SCHEMBL2018228 0.83 MEN1 (0.32) PPARG
SCHEMBL3737689 0.82 SGMS2 (0.34) PPARG
SCHEMBL28157161 0.82 TLR8 (0.35)
SCHEMBL118831 0.82 TLR8 (0.36)
SCHEMBL28561775 0.80 CNR1 (0.31)
SCHEMBL404717 0.78 SOAT1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126253-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, A SUITABLY SELECTED LIPOPHILIC POLYMER AND A CARRAGEENAN L'OREAL (FR) 2024-06-20 WO claimed
WO-2024106520-A1 NON-STICKY STABLE COMPOSITION WITH TEXTURE TRANSFORMATION PROPERTY L'OREAL (FR) 2024-05-23 WO claimed
EP-3393437-B1 PHOTOPROTECTIVE COMPOSITION BASED ON A CARBOXYLIC ACID ESTER; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR OREAL (FR) 2023-06-07 EP claimed
US-10918583-B2 Cosmetic or dermatological composition comprising a merocyanine, an organic UVB-screening agent and an additional organic UVA-screening agent L'OREAL (FR) 2021-02-16 US claimed
EP-3193816-B1 COMPOSITION BASED ON MULTILAYER SPHERICAL COMPOSITE PARTICLES AND ON A UV-SCREENING AGENT OREAL (FR) 2020-05-13 EP claimed
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF L'OREAL (FR) 2019-11-07 US claimed
EP-3197563-B1 COMPOSITION BASED ON A LIPOPHILIC ORGANIC UV-SCREENING AGENT AND A FILLER OREAL (FR) 2019-10-30 EP claimed
EP-2775994-B1 COMPOSITION WITH A CONTINUOUS OIL PHASE CONTAINING AT LEAST ONE LIPOPHILIC ORGANIC UV-SCREENING AGENT AND HYDROPHOBIC SILICA AEROGEL PARTICLES OREAL (FR) 2019-10-16 EP claimed
EP-3016631-B1 COSMETIC COMPOSITION OREAL (FR) 2019-10-02 EP claimed
US-10272021-B2 Composition based on multilayer spherical composite particles and on a UV-screening agent L'OREAL (FR) 2019-04-30 US claimed
WO-2013084184-A2 PHOTOPROTECTIVE AND SELF-TANNING COSMETIC EMULSIONS L'OREAL (FR) 2013-06-13 WO claimed
WO-2013068237-A1 COMPOSITION WITH A CONTINUOUS OIL PHASE CONTAINING AT LEAST ONE LIPOPHILIC ORGANIC UV-SCREENING AGENT AND HYDROPHOBIC SILICA AEROGEL PARTICLES L'OREAL (FR) 2013-05-16 WO claimed
US-20130058990-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'OREAL (FR) 2013-03-07 US claimed
EP-2547313-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'Oréal (FR) 2013-01-23 EP claimed
WO-2012168102-A2 ANHYDROUS ANTISUN CREAM COMPRISING A NON-EMULSIFYING ELASTOMERIC ORGANOPOLYSILOXANE, A MATTING AGENT AND A NON-SILICONE ORGANIC OIL THICKENER L'OREAL (FR) 2012-12-13 WO claimed
EP-2174644-B1 Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative OREAL (FR) 2012-11-14 EP claimed
WO-2011113718-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'OREAL (FR) 2011-09-22 WO claimed
US-20100172944-A1 COMBINATION OF MONOSACCHARIDES WITH SUNSCREENS AND USE THEREOF L'OREAL (FR) 2010-07-08 US claimed
US-20100086502-A1 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor L'OREAL (FR) 2010-04-08 US claimed
US-20090285868-A1 Photostable cosmetic compositions comprising dibenzoylmethane/pyrrolidinone compounds L'OREAL (FR) 2009-11-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF NQO1, LRAT, RBP4 PPARG 396/4885
US-20100086502-A1 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor NOTUM, DDT, FDFT1 PPARG 1289/4885
US-20090285868-A1 Photostable cosmetic compositions comprising dibenzoylmethane/pyrrolidinone compounds NOTUM, CYP51A1, DHPS PPARG 63/4885
US-10272021-B2 Composition based on multilayer spherical composite particles and on a UV-screening agent CUTA, RAD52, PSMC3 PPARG 4134/4885
US-20130058990-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT CRYZ, MSH6, TYR PPARG 2485/4885
US-10918583-B2 Cosmetic or dermatological composition comprising a merocyanine, an organic UVB-screening agent and an additional organic UVA-screening agent KRT18, CRYZ, CUTA PPARG 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.