Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 6/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31348109 | 0.95 | SMYD3 (0.42) | SMYD3DRD2DRD3DRD4HTR2A | |
| SCHEMBL31348234 | 0.89 | PRMT5 (0.43) | SMYD3DRD2DRD3DRD4HTR2A | |
| SCHEMBL31348255 | 0.79 | DRD2 (0.39) | SMYD3DRD2DRD3DRD4HTR2A | |
| SCHEMBL31348230 | 0.79 | SMYD3 (0.41) | SMYD3DRD2DRD3DRD4HTR2A | |
| SCHEMBL31348181 | 0.79 | DRD3 (0.56) | SMYD3DRD2DRD3DRD4HTR2A | |
| SCHEMBL31348122 | 0.76 | DRD3 (0.47) | SMYD3DRD2DRD3DRD4HTR2A | |
| SCHEMBL31348158 | 0.75 | DRD3 (0.57) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL31348183 | 0.74 | DRD3 (0.64) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL31348112 | 0.73 | PDE2A (0.40) | DRD2CCR2 | |
| SCHEMBL31348258 | 0.73 | PDE2A (0.40) | DRD2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006982-A1 | POTENT AND SELECTIVE DOPAMINE D3 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-02 | — | — | WO | disclosed |