Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | DRD3 | P35462 | 6/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31348169 | 0.86 | ABCB11 (0.37) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL31348234 | 0.81 | PRMT5 (0.43) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL31348129 | 0.79 | SMYD3 (0.42) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL31348230 | 0.77 | SMYD3 (0.41) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL31348109 | 0.77 | SMYD3 (0.42) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL31348200 | 0.74 | SMYD3 (0.37) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL31348113 | 0.73 | OPRL1 (0.46) | DRD2DRD3DRD4ABCB11TP53 | |
| SCHEMBL31348186 | 0.73 | OPRL1 (0.46) | DRD2DRD3DRD4ABCB11TP53 | |
| SCHEMBL31348183 | 0.72 | DRD3 (0.64) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL31348264 | 0.72 | OPRL1 (0.45) | DRD2DRD3ABCB11TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006982-A1 | POTENT AND SELECTIVE DOPAMINE D3 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-02 | — | — | WO | disclosed |