Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31348186 | 0.82 | OPRL1 (0.46) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL31348113 | 0.82 | OPRL1 (0.46) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL31348146 | 0.81 | ALDH1A1 (0.38) | OPRM1MAPK1SIGMAR1KDM4ESMN1; SMN2 | |
| SCHEMBL31348172 | 0.79 | OPRM1 (0.40) | OPRL1OPRM1OPRD1SCN1ASCN5A | |
| SCHEMBL31348261 | 0.73 | SCN1A (0.43) | MAPK1SCN1ASCN5ASCN9ADRD3 | |
| SCHEMBL31348255 | 0.72 | DRD2 (0.39) | OPRL1OPRM1ABCB11TP53CYP3A4 | |
| SCHEMBL31348169 | 0.72 | ABCB11 (0.37) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL31348260 | 0.70 | HSD17B2 (0.41) | MAPK1SCN1ASCN5ASCN9ASMN1; SMN2 | |
| SCHEMBL11811302 | 0.69 | MAPK1 (0.56) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL24484713 | 0.68 | KDM1A (0.48) | OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006982-A1 | POTENT AND SELECTIVE DOPAMINE D3 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-02 | — | — | WO | disclosed |