Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349222 | 0.87 | POLB (0.54) | SMN1; SMN2LMNAPOLBKMT2AMEN1 | |
| SCHEMBL31349219 | 0.83 | POLB (0.57) | POLBL3MBTL1PPARDPPARA | |
| SCHEMBL31349205 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAPOLBKMT2AMEN1 | |
| SCHEMBL31349227 | 0.80 | POLB (0.56) | SMN1; SMN2POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL31349214 | 0.80 | POLB (0.51) | SMN1; SMN2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL31349236 | 0.80 | POLB (0.53) | POLBKMT2AMEN1L3MBTL1PPARD | |
| SCHEMBL31349291 | 0.79 | POLB (0.57) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL31349299 | 0.79 | POLB (0.54) | POLBDRD4L3MBTL1 | |
| SCHEMBL31349298 | 0.79 | POLB (0.57) | SMN1; SMN2LMNAPOLBKMT2AMEN1 | |
| SCHEMBL31349209 | 0.78 | MEN1 (0.64) | SMN1; SMN2LMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |