Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349222 | 0.83 | POLB (0.54) | SMN1; SMN2LMNAMEN1KMT2APOLB | |
| SCHEMBL31349261 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31349240 | 0.80 | SLC6A9 (0.61) | SMN1; SMN2ALDH1A1LMNAHTTMEN1 | |
| SCHEMBL31349227 | 0.79 | POLB (0.56) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL31349219 | 0.78 | POLB (0.57) | POLB | |
| SCHEMBL31349306 | 0.77 | POLB (0.51) | LMNAMAPTPOLB | |
| SCHEMBL31349245 | 0.76 | POLB (0.55) | SMN1; SMN2ALDH1A1LMNAHTTMEN1 | |
| SCHEMBL31349298 | 0.76 | POLB (0.57) | SMN1; SMN2ALDH1A1LMNAHTTMEN1 | |
| SCHEMBL31349291 | 0.76 | POLB (0.57) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL31349251 | 0.74 | POLB (0.60) | LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |