SCHEMBL3134927

SCHEMBL3134927

CC[Hg]SOc1ccccc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.49
ALDH1A1 P00352 9/20 0.49
HSD17B10 Q99714 7/20 0.49
HPGD P15428 5/20 0.49
TDP1 Q9NUW8 2/20 0.49
ESR1 P03372 1/20 0.49
ITGB3 P05106 1/20 0.49
ITGA2B P08514 1/20 0.49
HMGB1 P09429 1/20 0.49
TSHR P16473 1/20 0.49
GGT1 P19440 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
BLM P54132 1/20 0.49
NAPRT Q6XQN6 1/20 0.49
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
RECQL P46063 1/20 0.48
HTT P42858 2/20 0.46
PTK2B Q14289 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6304663 0.98 KDM4E (0.47) KDM4EALDH1A1HSD17B10HPGDTDP1
SCHEMBL714867 0.84 KDM4E (0.40) KDM4EALDH1A1HPGDTSHRKMT2A
SCHEMBL1308799 0.79 KDM4E (0.54) KDM4EALDH1A1HSD17B10HPGDTDP1
SCHEMBL2964438 0.78 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDTDP1
SCHEMBL9217136 0.77 KDM4E (0.51) KDM4EALDH1A1HSD17B10HPGDTDP1
SCHEMBL11358522 0.76 KDM4E (0.56) KDM4EALDH1A1HSD17B10HPGDTDP1
SCHEMBL212177 0.75 KDM4E (0.58) KDM4EALDH1A1HSD17B10HPGDTDP1
SCHEMBL11281805 0.75 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDTDP1
SCHEMBL27931686 0.75 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDTDP1
SCHEMBL144897 0.75 KDM4E (0.57) KDM4EALDH1A1HSD17B10HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020051748-A1 STABILIZED WATER-IN-OIL-IN-WATER ANTIGEN DELIVERY SYSTEM MAINE BIOLOGICAL LABORATORIES 2002-05-02 US claimed
WO-2000037045-B1 STABILIZED WATER-IN-OIL-IN-WATER ANTIGEN DELIVERY SYSTEM MAINE BIOLOG LAB INC (US) 2000-11-23 WO claimed
WO-2000037045-A2 STABILIZED WATER-IN-OIL-IN-WATER ANTIGEN DELIVERY SYSTEM MAINE BIOLOGICAL LABORATORIES, INC. (US) 2000-06-29 WO claimed
US-5910427-A PROTEIN DERIVATIVES FORMED BY REPLACEMENT, SUBSTITUTION, OR CHEMICAL MODIFICATION OF AMINO ACIDS 57 AND/OR 60 HAVING INCREASED ACTIVITY; FOR IMMUNOSUPPRESSIVES/ALLERGY TREATMENTS LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 1999-06-08 US claimed
EP-0238657-B1 ANTIVIRAL IMMUNOTHERAPEUTIC AGENT AND PREPARATION THEREOF VETREPHARM RESEARCH, INC. (US) 1992-03-11 EP claimed
US-4959176-A ALKALI METAL SALT OF CITRIC ACID, ALKALI METAL NITRATE, NITRIC ACID BECKMAN INSTRUMENTS, INC. (US) 1990-09-25 US claimed
US-4070483-A Method of administering a human ocular treating agent and product therefor LERMAN SIDNEY 1978-01-24 US claimed
EP-4226937-A2 NON-NEUROINVASIVE VIRUSES AND USES THEREOF Northwestern University (US) 2023-08-16 EP disclosed
EP-4226936-A2 NON-NEUROINVASIVE VIRUSES AND USES THEREOF Northwestern University (US) 2023-08-16 EP disclosed
US-20230082744-A1 NON-NEUROINVASIVE VIRUSES AND USES THEREOF TRUSTEES OF TUFTS COLLEGE (A/K/A TUFTS UNIVERSITY) 2023-03-16 US disclosed
US-11447753-B2 Non-neuroinvasive viruses and uses thereof NORTHWESTERN UNIVERSITY (US) 2022-09-20 US disclosed
US-11339378-B2 Non-neuroinvasive viruses and uses thereof NORTHWESTERN UNIVERSITY (US) 2022-05-24 US disclosed
US-20210330611-A1 THERAPY FOR NEUROLOGICAL DISEASES/DISORDERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-10-28 US disclosed
US-4203802-A ENZYME BOUND TO AN ESTROGEN LIGAND SYVA COMPANY (US) 1980-05-20 US disclosed
US-4196201-A Non-irritating eye make-up remover composition L'OREAL (FR) 1980-04-01 US disclosed
US-4190496-A RECEPTOR, LIGAND, AND ENZYME-BOUND SYVA COMPANY (US) 1980-02-26 US disclosed
US-4070483-A Method of administering a human ocular treating agent and product therefor LERMAN SIDNEY 1978-01-24 US disclosed
US-4067774-A Compounds for enzyme amplification assay SYVA COMPANY (US) 1978-01-10 US disclosed
US-3975237-A LIGANDS SYVA COMPANY (US) 1976-08-17 US disclosed
US-3966556-A Compounds for enzyme amplification assay methadone analogs SYVA COMPANY (US) 1976-06-29 US disclosed