Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134927 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL6304663 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL2844163 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1HPGDLTB4RLTB4R2 | |
| SCHEMBL5404188 | 0.78 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL5709037 | 0.74 | HCRTR1 (0.60) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL31721706 | 0.74 | HCRTR1 (0.60) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL8156346 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL29357453 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL3525 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL20582713 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090169424-A1 | Method of disinfecting and wetiing the interior of a building | FRANCHI RICHARD MICHAEL | 2009-07-02 | — | — | US | claimed |
| WO-2007117565-A9 | STANDARDIZATION OF PROCESSES FOR CULTURING PRIMARY CELLS | CHI SCIENT INC (US) | 2007-12-27 | — | — | WO | claimed |
| WO-2007117565-A2 | STANDARDIZATION OF PROCESSES FOR CULTURING PRIMARY CELLS | CHI SCIENTIFIC, INC. (US) | 2007-10-18 | — | — | WO | claimed |
| US-20070238175-A1 | Standardization of processes for culturing primary cells | CHI SCIENTIFIC, INC. | 2007-10-11 | — | — | US | claimed |
| EP-1161265-A4 | METHOD FOR THE IDENTIFICATION AND REMOVAL OF NITS FROM HAIR | REID LORI FOX (US) | 2006-01-11 | — | — | EP | claimed |
| US-6942875-B2 | Applying polymerizable monomer and fungicide; applying to skins | CLOSURE MEDICAL CORPORATION (US) | 2005-09-13 | — | — | US | claimed |
| US-20040151688-A1 | Adhesive treatment for epistaxis | CLOSURE MEDICAL CORPORATION (US) | 2004-08-05 | — | — | US | claimed |
| US-6767552-B2 | Adhesive treatment for oral fungal infection | CLOSURE MEDICAL CORPORATION | 2004-07-27 | — | — | US | claimed |
| US-6602496-B2 | Applying polymerizable monomer and fungicide; applying to skins | CLOSURE MEDICAL CORPORATION | 2003-08-05 | — | — | US | claimed |
| US-6585967-B2 | Adhesive treatment for tinea cruris | CLOSURE MEDICAL CORPORATION | 2003-07-01 | — | — | US | claimed |
| US-5044141-A | Method for sterile packaging and wetting of articles | FRANCHI TECHNOLOGY CORPORATION | 1991-09-03 | — | — | US | claimed |
| EP-0209192-B1 | CONTACT-LENS LIQUID | ICN PHARMACEUTICALS HOLLAND B.V. (NL) | 1991-06-05 | — | — | EP | claimed |
| US-4715982-A | NONIRRITATING | L'OREAL (FR) | 1987-12-29 | — | — | US | claimed |
| EP-0209192-A1 | Contact-lens liquid | ICN PHARMACEUTICALS HOLLAND B.V. (NL) | 1987-01-21 | — | — | EP | claimed |
| EP-0053451-B1 | CONTACT LENS DISINFECTING AND PRESERVING SOLUTION (POLYMERIC) | BAUSCH & LOMB INCORPORATED (US) | 1985-03-13 | — | — | EP | claimed |
| EP-0037043-B1 | STABILISED OPHTHALMIC FORMULATION | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | claimed |
| US-4421748-A | LECITHIN AND VISCOSITY-ADJUSTING AGENT | TRAGER SEYMOUR F | 1983-12-20 | — | — | US | claimed |
| EP-0037043-A1 | Stabilised ophthalmic formulation | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-07 | — | — | EP | claimed |
| US-4252826-A | CARBOXYLATE OF A METHYL POLYETHOXYLATED GLUCOSIDE AND A PRESERVATIVE AGENT | L'OREAL (FR) | 1981-02-24 | — | — | US | claimed |
| US-4013576-A | AMPHOTERIC SURFACTANT | WESLEY-JESSEN INC. (US) | 1977-03-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040151688-A1 | Adhesive treatment for epistaxis | ICAM1, ELANE, EPCAM | KDM4E 3861/4885ALDH1A1 2011/4885HPGD 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.