Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CPB1 | P15086 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344554 | 0.89 | CTSK (0.52) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL19100272 | 0.85 | CTSK (0.51) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL13738193 | 0.85 | CTSK (0.51) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL19100142 | 0.85 | CTSK (0.51) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL19063792 | 0.84 | CTSK (0.58) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL4364990 | 0.84 | CTSK (0.58) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL4366638 | 0.84 | CTSK (0.58) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL9993970 | 0.84 | CTSK (0.58) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL745942 | 0.84 | CTSK (0.58) | CTSKCPB1ALDH1A1GAACTSL | |
| SCHEMBL14820339 | 0.83 | ALDH1A1 (0.62) | CTSKCPB1ALDH1A1GAACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |