Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | RAD52 | P43351 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350638 | 0.81 | KDM4E (0.45) | ALDH1A1POLBKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL31350548 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4EKMT2ASMN1; SMN2HTT | |
| SCHEMBL31350461 | 0.78 | XDH (0.42) | ALDH1A1POLBKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL31350904 | 0.78 | NOS3 (0.36) | ALDH1A1POLBSMN1; SMN2MAPTRAB9A | |
| SCHEMBL31350697 | 0.74 | ALDH1A1 (0.39) | ALDH1A1POLBKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL31350703 | 0.72 | ALDH1A1 (0.44) | ALDH1A1POLBKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL3255147 | 0.71 | CCR1 (0.33) | L3MBTL1 | |
| SCHEMBL31350484 | 0.69 | KDM4E (0.45) | ALDH1A1POLBKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL31350740 | 0.69 | KDM4E (0.49) | ALDH1A1POLBKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL390428 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025133613-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDO-PYRIMIDINE CORE AND A (HETERO)AROMATIC-AMINO SUBSTITUENT | Tay Therapeutics Limited (GB) | 2025-06-26 | — | — | WO | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |