Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17591608 | 0.81 | EGFR (0.37) | CHEK1EGFRCYP11B1CYP11B2ERBB2 | |
| SCHEMBL19328130 | 0.79 | PGK1 (0.44) | CHEK1EGFRERBB2ALDH1A1MAPT | |
| SCHEMBL4099333 | 0.78 | DYRK1A (0.41) | EGFRERBB2DYRK1ALRRK2DYRK1B | |
| SCHEMBL31350683 | 0.78 | OPRK1 (0.36) | EGFRCYP11B1CYP11B2ERBB2KDR | |
| SCHEMBL31350596 | 0.78 | OPRK1 (0.36) | EGFRCYP11B1CYP11B2ERBB2KDR | |
| SCHEMBL19327981 | 0.77 | PDE10A (0.45) | CHEK1EGFRERBB2LRRK2ALDH1A1 | |
| SCHEMBL19328050 | 0.76 | USP2 (0.40) | PRKCQLRRK2CLK4ALDH1A1CYP1A2 | |
| SCHEMBL19328092 | 0.75 | SMN1; SMN2 (0.47) | EGFRERBB2CDK8ALDH1A1MAPT | |
| SCHEMBL29477047 | 0.75 | CCNA2 (0.48) | EGFRAURKAALDH1A1MAPTCYP1A2 | |
| SCHEMBL27241771 | 0.75 | EGFR (0.41) | EGFRERBB2KDRALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |