Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350683 | 1.00 | OPRK1 (0.36) | OPRK1CYP11B1CYP11B2GLAKDM4E | |
| SCHEMBL31350832 | 0.78 | CHEK1 (0.37) | CYP11B1CYP11B2GLAKDM4EMEN1 | |
| SCHEMBL7215518 | 0.74 | CHRNB2 (0.42) | OPRK1CYP11B1CYP11B2KDM4ENPSR1 | |
| SCHEMBL31350552 | 0.74 | SMN1; SMN2 (0.40) | CYP11B1CYP11B2KDM4EGAAMEN1 | |
| SCHEMBL11617655 | 0.74 | GPR35 (0.41) | GLAKDM4EGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11782988 | 0.73 | CNR1 (0.44) | GLAKDM4EGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL21928132 | 0.72 | CYP11B1 (0.38) | OPRK1CYP11B1CYP11B2KDM4ENPSR1 | |
| SCHEMBL12772274 | 0.72 | CDK1 (0.36) | OPRK1CYP11B1CYP11B2KDM4ENPSR1 | |
| SCHEMBL625135 | 0.71 | NOS3 (0.54) | CYP11B1CYP11B2KDM4ENPSR1RXFP1 | |
| SCHEMBL3651726 | 0.71 | NOS3 (0.39) | OPRK1CYP11B1CYP11B2KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |