Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094892 | 0.82 | KDM4E (0.43) | ENPP2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL7555630 | 0.77 | GAA (0.48) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL16532144 | 0.72 | HSD17B10 (0.39) | KDM4EALDH1A1HPGDCYP2C9CYP1A2 | |
| SCHEMBL2902981 | 0.70 | L3MBTL1 (0.40) | KDM4ECCR1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3135975 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL19208077 | 0.69 | ADORA3 (0.40) | ENPP2KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL13172345 | 0.67 | KDM4E (0.39) | KDM4EHDAC6ALDH1A1 | |
| SCHEMBL31105945 | 0.67 | KDM4E (0.36) | ENPP2KDM4EHDAC6ALDH1A1KMT2A | |
| SCHEMBL25925090 | 0.67 | ALDH1A1 (0.36) | ENPP2KDM4EHDAC6ALDH1A1L3MBTL1 | |
| SCHEMBL26454238 | 0.67 | ALDH1A1 (0.39) | ENPP2KDM4EHDAC6ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054427-B1 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-14 | — | — | EP | disclosed |
| EP-2054427-A2 | AVERMECTIN DERIVATIVES | Bayer CropScience AG (DE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008019784-A2 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |