Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075414 | 0.82 | TSHR (0.38) | TSHRCYP3A4ALDH1A1KDM4EMEN1 | |
| SCHEMBL7663273 | 0.81 | CYP4F2 (0.44) | PKMCYP4F2CYP4A11TSHRABCB11 | |
| SCHEMBL20098855 | 0.81 | PKM (0.46) | PKMCYP4F2CYP4A11TSHRABCB11 | |
| SCHEMBL2915795 | 0.78 | PKM (0.43) | PKMCYP4F2CYP4A11TSHRABCB11 | |
| SCHEMBL79003 | 0.78 | PKM (0.43) | PKMCYP4F2CYP4A11TSHRABCB11 | |
| SCHEMBL3135439 | 0.77 | PKM (0.42) | PKMCYP4F2CYP4A11TSHRABCB11 | |
| SCHEMBL26295367 | 0.76 | MGAM (0.44) | PKMCYP4F2CYP4A11CYP1A2ALDH1A1 | |
| SCHEMBL7667823 | 0.76 | — | — | |
| SCHEMBL13892163 | 0.75 | PKM (0.41) | PKMCYP4F2CYP4A11TSHRABCB11 | |
| SCHEMBL9796967 | 0.75 | PKM (0.41) | PKMCYP4F2CYP4A11TSHRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697388-B1 | METHOD FOR PRODUCING PHOSPHONIUM SALTS | BASF SE (DE) | 2010-07-21 | — | — | EP | disclosed |
| US-7547807-B2 | Method for producing phosphonium salts | BASF SE (DE) | 2009-06-16 | — | — | US | disclosed |
| US-20070123726-A1 | Method for producing phosphonium salts | BASF AKTIENGESELLSCHAFT PATENTS, TRADEMARKS AND LICENSES (DE) | 2007-05-31 | — | — | US | disclosed |
| EP-1697388-A1 | METHOD FOR PRODUCING PHOSPHONIUM SALTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058924-A1 | METHOD FOR PRODUCING PHOSPHONIUM SALTS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-30 | — | — | WO | disclosed |
| CN-1124257-C | 2-chloro-2-methyl-3-crotonization and 2-chloro-2-methyl-3-alkyl butenate | HOFFMANN LA ROCHE (CH) | 2003-10-15 | — | — | CN | disclosed |
| CN-1080266-C | Preparation of Wittig ester salts | HOFFMANN LA ROCHE (CH) | 2002-03-06 | — | — | CN | disclosed |
| CN-1269356-A | 2-chloro-2-methyl-3-crotonization and 2-chloro-2-methyl-3-alkyl butenate | HOFFMANN LA ROCHE (CH) | 2000-10-11 | — | — | CN | disclosed |
| US-5777149-A | Method for the production of (3-alkoxycarbonyl-2-butenyl) triphenylphosphonium salts | ROCHE VITAMINS INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5681977-A | Method for the production of (3-alkoxycarbonyl-2-butenyl) triphenylphosphonium salts | ROCHE VITAMINS INC. (US) | 1997-10-28 | — | — | US | disclosed |
| US-5631398-A | Method for the production of (3-alkoxycarbonyl-2-butenyl) triphenylphosphonium salts | ROCHE VITAMINS INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5502236-A | Method for the production of (3-alkoxycarbonyl-2-butenyl)triphenylphosphonium salts | HOFFMANN-LA ROCHE INC. (US) | 1996-03-26 | — | — | US | disclosed |
| CN-1115762-A | Preparation of Wittig ester salts | HOFFMANN LA ROCHE (CH) | 1996-01-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123726-A1 | Method for producing phosphonium salts | PHOSPHO1, PLIN5, SQLE | PKM 1118/4885CYP4F2 1035/4885CYP4A11 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.