Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13112959 | 0.90 | HCAR2 (0.41) | PKMCYP4F2CYP4A11ALDH1A1HCAR2 | |
| SCHEMBL9040519 | 0.84 | PKM (0.48) | PKMCYP4F2CYP4A11ALDH1A1HCAR2 | |
| SCHEMBL2918118 | 0.83 | PKM (0.41) | PKMCYP4F2CYP4A11ALDH1A1MMP8 | |
| SCHEMBL2918114 | 0.83 | PKM (0.41) | PKMCYP4F2CYP4A11ALDH1A1MMP8 | |
| SCHEMBL79003 | 0.82 | PKM (0.43) | PKMCYP4F2CYP4A11ALDH1A1HCAR2 | |
| SCHEMBL3135439 | 0.80 | PKM (0.42) | PKMCYP4F2CYP4A11ALDH1A1HCAR2 | |
| SCHEMBL2914630 | 0.80 | PKM (0.42) | PKMCYP4F2CYP4A11ALDH1A1HCAR2 | |
| SCHEMBL2917530 | 0.80 | PKM (0.42) | PKMCYP4F2CYP4A11ALDH1A1HCAR2 | |
| SCHEMBL26295367 | 0.79 | MGAM (0.44) | PKMCYP4F2CYP4A11ALDH1A1HCAR2 | |
| SCHEMBL3127139 | 0.78 | PKM (0.41) | PKMCYP4F2CYP4A11ALDH1A1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225382-B1 | NEW MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2016-11-09 | — | — | EP | disclosed |
| US-20150147800-A1 | MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2015-05-28 | — | — | US | disclosed |
| US-8951750-B2 | Malonate decarboxylases for industrial applications | BASF SE (DE) | 2015-02-10 | — | — | US | disclosed |
| EP-2565273-A1 | New malonate decarboxylases for industrial applications | BASF SE (DE) | 2013-03-06 | — | — | EP | disclosed |
| EP-2565274-A1 | New malonate decarboxylases for industrial applications | BASF SE (DE) | 2013-03-06 | — | — | EP | disclosed |
| US-20100311037-A1 | MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2010-12-09 | — | — | US | disclosed |
| EP-2225382-A2 | NEW MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009068308-A2 | NEW MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2009-06-04 | — | — | WO | disclosed |
| EP-0433024-B1 | Colour recording medium containing leuco dye | FUJI PHOTO FILM CO LTD (JP) | 1994-09-21 | — | — | EP | disclosed |
| EP-0433024-A1 | Colour recording medium containing leuco dye | FUJI PHOTO FILM CO., LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311037-A1 | MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | ME1, AMD1, GMDS | PKM 617/4885CYP4F2 2388/4885CYP4A11 2643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.