Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29650742 | 0.81 | ACHE (0.47) | ACHEBCHEGRIN1GRIN2AMPO | |
| SCHEMBL30661688 | 0.76 | DCPS (0.46) | ACHEBCHECHRM1GRIN1GRIN2A | |
| SCHEMBL29138830 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL29236344 | 0.73 | KDM4E (0.36) | — | |
| SCHEMBL30283755 | 0.72 | ACHE (0.45) | ACHELMNACYP1A2 | |
| SCHEMBL24468604 | 0.71 | KDM4E (0.35) | ACHEMAPTPOLBKMT2A | |
| SCHEMBL29650879 | 0.71 | KDM4E (0.35) | ACHEMAPTPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL26918508 | 0.70 | ACHE (0.32) | ACHE | |
| SCHEMBL31253292 | 0.69 | KDM4E (0.41) | ACHEBCHEGRIN1GRIN2AMAPT | |
| SCHEMBL29138919 | 0.69 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143752-A | Aminoquinoline derivative, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-12-17 | — | — | CN | disclosed |