Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 3/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31353075 | 0.94 | WNT3A (0.50) | WNT3ATNKS2METAP2PARP1PARP2 | |
| SCHEMBL6069754 | 0.80 | MAPT (0.51) | TNKS2METAP2PARP1PARP2CCNB2 | |
| SCHEMBL6407884 | 0.80 | HSD17B10 (0.51) | TNKS2METAP2PARP1PARP2CCNB2 | |
| SCHEMBL30273069 | 0.73 | HPGD (0.51) | TNKS2PARP1PARP2ALDH1A1HSD17B10 | |
| SCHEMBL10153752 | 0.68 | PARP1 (0.56) | TNKS2METAP2PARP1CCNB2CDK1 | |
| SCHEMBL30273158 | 0.67 | PARP1 (0.51) | PARP1PARP2 | |
| SCHEMBL29203629 | 0.67 | PARP1 (0.56) | PARP1ALDH1A1HSD17B10 | |
| SCHEMBL30273133 | 0.67 | PARP1 (0.41) | PARP1PARP2 | |
| SCHEMBL6554641 | 0.66 | PARP1 (0.53) | PARP1PARP2 | |
| SCHEMBL1003250 | 0.66 | LMNA (0.78) | CCNB2CDK1CCNB1GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143752-A | Aminoquinoline derivative, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-12-17 | — | — | CN | disclosed |