Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20227729 | 0.89 | PARP1 (0.62) | PARP1METAP2CDK9CDK5CAMK2A | |
| SCHEMBL12658618 | 0.88 | PARP1 (0.49) | PARP1METAP2CDK9CDK5CAMK2A | |
| SCHEMBL20227579 | 0.87 | PARP1 (0.66) | PARP1METAP2CDK9CDK5CAMK2A | |
| SCHEMBL30466768 | 0.87 | PARP1 (0.66) | PARP1METAP2CDK9CDK5CAMK2A | |
| SCHEMBL7610608 | 0.81 | CASP7 (0.72) | PARP1METAP2CDK9CDK5CAMK2A | |
| SCHEMBL29397381 | 0.80 | METAP2 (0.52) | METAP2CDK9CDK5CAMK2AJAK2 | |
| SCHEMBL28272924 | 0.80 | METAP2 (0.52) | METAP2CDK9CDK5CAMK2AJAK2 | |
| SCHEMBL181890 | 0.80 | METAP2 (0.52) | METAP2CDK9CDK5CAMK2AJAK2 | |
| SCHEMBL30013301 | 0.80 | METAP2 (0.60) | PARP1METAP2CDK9CDK5CAMK2A | |
| SCHEMBL2730824 | 0.80 | METAP2 (0.60) | PARP1METAP2CDK9CDK5CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-11713319-B2 | Compounds having valerolactam structures | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| WO-2023110742-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| EP-3548467-B1 | COMPOUNDS HAVING VALEROLACTAM STRUCTURES | MERCK PATENT GMBH (DE) | 2023-06-21 | — | — | EP | disclosed |
| EP-3548467-B1 | COMPOUNDS HAVING VALEROLACTAM STRUCTURES | MERCK PATENT GMBH (DE) | 2023-06-21 | — | — | EP | disclosed |
| US-20200031827-A1 | COMPOUNDS HAVING VALEROLACTAM STRUCTURES | MERCK PATENT GMBH (DE) | 2020-01-30 | — | — | US | disclosed |
| WO-2018099846-A1 | COMPOUNDS HAVING VALEROLACTAM STRUCTURES | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | WO | disclosed |
| US-20120008068-A1 | POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20120008068-A1 | POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |
| US-8012603-B2 | Polyanilines; strong fluorescence and large charge transporting properties | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8012603-B2 | Polyanilines; strong fluorescence and large charge transporting properties | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-06 | — | — | US | disclosed |
| EP-2325224-A1 | Aryl copolymer compounds and polymer light emitting devices made by using the same | Sumitomo Chemical Company, Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| EP-2325226-A1 | Complex aryl copolymer compounds and polymer light emitting devices made by using the same | Sumitomo Chemical Company, Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-20080138651-A1 | Polyanilines; strong fluorescence and large charge transporting properties | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-06-12 | — | — | US | disclosed |
| US-20080138651-A1 | Polyanilines; strong fluorescence and large charge transporting properties | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | ACE, CYP3A4, CYP2D6 | PARP1 340/4885METAP2 1163/4885CDK9 515/4885 |
| US-20080138651-A1 | Polyanilines; strong fluorescence and large charge transporting properties | BRS3, SLC43A1, MRPS23 | PARP1 341/4885METAP2 4075/4885CDK9 2986/4885 |
| US-20200031827-A1 | COMPOUNDS HAVING VALEROLACTAM STRUCTURES | ACE, CYP3A4, CYP2D6 | PARP1 340/4885METAP2 1163/4885CDK9 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.