Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034874 | 0.88 | PARP1 (0.62) | PARP1PARP2SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7111338 | 0.85 | PARP1 (0.80) | PARP1PARP2ALDH1A1 | |
| SCHEMBL26523318 | 0.78 | PARP1 (0.43) | PARP1PARP2SMN1; SMN2KMT2AKDR | |
| SCHEMBL1035340 | 0.78 | CYP2C9 (0.58) | NPC1RAB9AKMT2AALDH1A1MCL1 | |
| SCHEMBL7039533 | 0.77 | PARP1 (0.60) | PARP1PARP2ALDH1A1 | |
| SCHEMBL15940790 | 0.77 | ALDH1A1 (0.51) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL15228747 | 0.77 | PARP1 (0.43) | PARP1PARP2SMN1; SMN2KMT2AKDR | |
| SCHEMBL1032829 | 0.77 | CHRNB2 (0.61) | PARP1PARP2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28221938 | 0.76 | NPC1 (0.60) | PARP1NPC1RAB9ASMN1; SMN2PDGFRB | |
| SCHEMBL15228669 | 0.76 | HTT (0.55) | PARP1NPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |