Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135399 | 1.00 | KMT2A (0.58) | KMT2AMEN1ATMPDE4BNPSR1 | |
| SCHEMBL3135418 | 1.00 | KMT2A (0.58) | KMT2AMEN1ATMPDE4BNPSR1 | |
| SCHEMBL7862697 | 0.88 | NLRP3 (0.64) | KMT2AMEN1PDE4BNPSR1AKR1B1 | |
| SCHEMBL24129903 | 0.88 | CISD1 (0.67) | KMT2AMEN1ATMPDE4BNPSR1 | |
| SCHEMBL2447131 | 0.88 | CISD1 (0.67) | KMT2AMEN1ATMPDE4BNPSR1 | |
| SCHEMBL2447134 | 0.88 | CISD1 (0.67) | KMT2AMEN1ATMPDE4BNPSR1 | |
| SCHEMBL25152291 | 0.83 | MAOA (0.57) | KMT2AMEN1ATMAKR1B1MMP3 | |
| SCHEMBL25151800 | 0.82 | MAOA (0.56) | KMT2AMEN1ATMAKR1B1CISD1 | |
| SCHEMBL30330275 | 0.82 | MAOA (0.56) | KMT2AMEN1ATMAKR1B1CISD1 | |
| SCHEMBL23578641 | 0.81 | PDE4B (0.61) | KMT2AMEN1PDE4BAKR1B1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | MAVS, LAMP1, HAVCR2 | KMT2A 2561/4885MEN1 4512/4885ATM 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.